Plant Transcription Factor Database
Previous version: v3.0
Nicotiana benthamiana
BES1 Family
Species TF ID Description
Niben101Scf00073g05010.1BES1 family protein
Niben101Scf00219g06001.1BES1 family protein
Niben101Scf00894g00004.1BES1 family protein
Niben101Scf00929g03010.1BES1 family protein
Niben101Scf01983g15010.1BES1 family protein
Niben101Scf03110g05009.1BES1 family protein
Niben101Scf03282g02006.1BES1 family protein
Niben101Scf03729g00010.1BES1 family protein
Niben101Scf04132g01002.1BES1 family protein
Niben101Scf04981g00008.1BES1 family protein
Niben101Scf05540g00014.1BES1 family protein
Niben101Scf05948g02026.1BES1 family protein
Niben101Scf06112g01006.1BES1 family protein
Niben101Scf07346g04001.1BES1 family protein
Niben101Scf07509g01008.1BES1 family protein
Niben101Scf10196g01002.1BES1 family protein
Niben101Scf10412g00006.1BES1 family protein
Niben101Scf10441g01004.1BES1 family protein
Niben101Scf10887g01009.1BES1 family protein
Niben101Scf12841g03023.1BES1 family protein
BES1 Family Introduction

Brassinosteroids (BRs) signal through a plasma membrane-localized receptor kinase to regulate plant growth and development. We showed previously that a novel protein, BES1(BRI1-EMS-SUPPRESSOR 1), accumulates in the nucleus in response to BRs, where it plays a role in BR-regulated gene expression; however, the mechanism by which BES1 regulates gene expression is unknown. In this study, we dissect BES1 subdomains and establish that BES1 is a transcription factor that binds to and activates BR target gene promoters both in vitro and in vivo. BES1 interacts with a basic helix-loop-helix protein, BIM1, to synergistically bind to E box (CANNTG) sequences present in many BR-induced promoters. Loss-of-function and gain-of-function mutants of BIM1 and its close family members display BR response phenotypes. Thus, BES1 defines a new class of plant-specific transcription factors that cooperate with transcription factors such as BIM1 to regulate BR-induced genes.

Yin Y, Vafeados D, Tao Y, Yoshida S, Asami T, Chory J.
A new class of transcription factors mediates brassinosteroid-regulated gene expression in Arabidopsis.
Cell. 2005 Jan 28;120(2):249-59.
PMID: 15680330